CBD as such has been found to be useful to us and can cure a number of medical problems however it always remains a concern whether CBD can be taken along with other medications. How cannabis works in our body along with any medicine is not known.
CBD wholesale is also a chemical compound and it can certainly react with any other medicines that are chemicals. Most of the prescription medicines clearly mention in their label about the things to avoid along with the medication.
CBD as such can also work with many medicines, but with certain medicines it may also work adversely on the body. Therefore, it is essential that before you take any CBD supplement with any medication, you must consult with your doctor too.
CBD and drug interaction
While discussing about the interactions between CBD and any drug then these can always be broken into 2 basic categories.
1. Those drugs that may create dangerous interaction, and hence should never be combined with CBD
2. Next drugs are those that simply needs you to be little cautious while combining with CBD.
There are 2 drugs that one should never take with CBD oils are –
2. Valproic acid.
If you take CBD with clobazam then it can intensify the working of this drug and as a result it will also increase its side effects. If you combine valproic acid along with CBD then it could cause liver injury.
The next category of drugs will be those that require using little caution while taking them along with CBD.
Many prescriptions may also fall into these types of medicines as they either will increase or decrease the speed at which your liver enzymes can break down your drugs, hence it can either reduce or intensify their effect.
Many of these drugs are either cytochrome P450-enzymes, or CYP450s. Therefore, in case you are taking any kind of prescription drug that falls in the category of CYP450 enzymes, then it is best to talk to your doctor before starting to take CBD supplements.
List of those drugs are as follows:
- CYP1A1 substrates
- CYP1A2 substrates
- CYP1B1 substrates
- CYP2A6 substrates
- CYP2B6 substrates
- CYP2C19 substrates
- CYP2C8 substrates
- CYP2C9 substrates
- CYP2D6 substrates
- CYP3A4 substrates
- CYP3A5 substrates
- CYP2C19 inhibitors
- CYP3A4 inhibitors
- CYP3A4 inducers
- CYP2C19 inducers
- Glucuronidated drugs
If we try to sum up all that we discussed above, those of you who are taking any of the above medications must consult your healthcare provider prior to taking CBD oil.
Besides that, in addition to providing you guidance, whether the CBD will be safe for you to take, your doctor can also offer you medical advice as far as CBD dose is concerned, so that you can get more effective results without getting any kind of adverse effects.
In few cases, they may also suggest you to start with very low CBD dose in the beginning and move to higher dose once you are sure that CBD is safe for you.